Montreal Back Pain Related to Inflammation Reduced with Melatonin
Inflammation. Disc Degeneration. There is a relationship. Inflammation is the body’s response to damaging stimuli (injury, pathogens, metabolic stress – a disc herniation pushing on a nerve!) as it tries to restore itself to normal before the harm was done. Dr. Hoang's Chiropractic Clinic is always amazed at what the body can do! Dr. Hoang's Chiropractic Clinic sees its Montreal chiropractic care as a partner of the body’s system in healing particularly when spine pain is an issue. Chiropractic care utilizes many tools like spinal manipulation, exercise, and nutrition to take care of the body. Melatonin is one nutritional tool that is showing value in its ability to interrupt the inflammatory process related disc herniation that results in back pain, neck pain and other spine related pain.
DISC DEGENERATION AND INFLAMMATION AND 'AUTOPHAGY'
Inflammatory markers interleukin-1β (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) are linked to intervertebral disc degeneration. (1) IL-1 β in fact promotes itself, its own expression, by upregulating NLRP3 inflammasome activation. (2) The body regulates itself down to its cellular level via autophagy, the natural process during which the body’s cells clear out damaged (ie, by inflammation) or unneeded parts. In a new study, melatonin boosted autophagy and decreased the degradation of the disc’s extracellular matrix (technically indicated by a decrease in marker LC3B, autophagasomes and autolysosomes and inhibition of the NF-kB signaling pathway). The final conclusion was that melatonin prevents intervertebral disc degeneration by stimulating autophagy. (3) Wow. Dr. Hoang's Chiropractic Clinic is encouraged by this research to see just how well melatonin can perform for Montreal back pain related to disc degeneration.
MELATONIN AND ITS HEALING WAYS FOR THE DISC
Disc degeneration is a very common malady seen at Dr. Hoang's Chiropractic Clinic that positive news of melatonin’s benefits are quite rousing. A recent study stated that melatonin could modulate the extracellular matrix of the disc remodeling process started by IL-1 β. Additionally, melatonin decreased the inflammatory cell collection and reduced the release of associated inflammatory markers IL-1β, IL-6, and TNF-α. With this new finding that melatonin interrupted the IL-1B feedback loop, researchers proposed that melatonin may provide the restoration process of intervertebral discs after damage has already been done. (1) Dr. Hoang's Chiropractic Clinic continues following the new research regarding the role inflammation performs in Montreal disc degeneration and melatonin’s role in reducing it.
INFLAMMATION AND MELATONIN
The importance of melatonin in assisting to slow or stop painful conditions due to inflammation is rising. The description of melatonin as a multitasking molecule influencing mood, immunity, and energy among other things is quite appropriate. It is also anti-oxidant, anti-aging, and anti-inflammatory, specifically by blocking the activation of inflammasomes (4) Melatonin’s formal chemical name is as about as long as its list of tasks: N-acetyl-5-methoxytryptamine. The pineal gland secretes melatonin naturally. Melatonin impacts the body’s aging, anti-inflammatory, anti-apoptosis (cell death), and autophagy (cell-cleanout) activities. (1) Melatonin’s specific effect on inflammation and disc degeneration is most interesting to Dr. Hoang's Chiropractic Clinic and our Montreal back pain patients.
CONTACT Dr. Hoang's Chiropractic Clinic
Listen to this PODCAST with Dr. Hrefna Sylvia based in Iceland where back pain isn’t much different from any other country on The Back Doctors Podcast with Dr. Michael Johnson as she illustrates how The Cox® Technic System of Spinal Pain Management addresses disc degeneration for relief of chronic low back pain in her patient.
Schedule your Montreal chiropractic appointment with Dr. Hoang's Chiropractic Clinic today. We can talk about the role inflammation plays in your back pain experience and how melatonin may address the related disc degeneration.
